Complex Regional Pain Syndrome

Complex regional pain syndrome (CRPS) is a devastating posttraumatic neuroinflammatory condition with both autoinflammatory and autoimmune features, characterized by unrelenting severe pain and disability, with the majority of affected patients being unable to function socially or vocationally. Research has shown patients with dramatic responses to hyperbaric oxygen therapy (HBOT). HBOT has been shown to be effective in long-standing CRPS, both initially, and for subsequent flares. HBOT’s ability to induce all stages of wound healing through reducing inflammation, enhancing stem cell release up to 800%, supersaturating tissues with up to 1200% plasma oxygen, stimulating fibroblast production, and promoting angiogenesis among others positions HBOT as a viable option for these patients.

“….A 41-year-old male with one-year history of CRPS of left foot followed by left ankle fracture demonstrated less pain, decreased swelling, less allodynia, and improvement in skin color and range of motion of the lower limb after 3 weeks of HBOT. Patient was back to work for the first time in over a year. HBOT may be considered as a valuable therapeutic tool in the treatment of long-standing CRPS….”

“…A broad spectrum of conditions including neuropathic pain, complex regional pain syndrome (CRPS) and fibromyalgia, have been implicated as causes of chronic pain. There is a need for new and effective treatments that patients can tolerate without significant adverse effects. One potential intervention is hyperbaric oxygen treatment (HBOT)….”

The Effectiveness of Hyperbaric Oxygen Treatment in Patients with Complex Regional Pain Syndrome: A Retrospective Case series https://pubmed.ncbi.nlm.nih.gov/39239556/

Successful Treatment of Long Standing Complex Regional Pain Syndrome with Hyperbaric Oxygen Therapy https://pubmed.ncbi.nlm.nih.gov/31838618/

Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy https://pubmed.ncbi.nlm.nih.gov/27445607/

Hyperbaric oxygen treatment in recurrent development of complex regional pain syndrome: A case report https://pubmed.ncbi.nlm.nih.gov/33761551/

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