PTSD/Anxiety/Depression
PTSD, anxiety, and depression secondary to microstructural neurological changes can be substantially improved through Hyperbaric oxygen therapy. Some research suggests that PTSD can no longer be considered strictly a psychiatric disease as it is always accompanied with neuroplastic changes throughout the brain. Hyperbaric can heal associated brain dysfunction through its ability to induce neuroplasticity, angiogenesis, stem cell release (up to 800%), growth hormones, immune modulation, and supersaturate tissue up with plasma oxygen (up to 1200% increase). It is important to remember that HBOT is an adjunctive treatment to therapy and various psychiatric treatments and is not suggested to be a stand alone application.
Hyperbaric oxygen: B-level evidence in mild traumatic brain injury clinical trials https://pubmed.ncbi.nlm.nih.gov/27581219/
“…..(hyperbaric oxygen therapy) can alleviate posttraumatic stress disorder symptoms secondary to a brain injury in 5 out of 5 peer-reviewed clinical trials.”
Hyperbaric Oxygen Therapy for Veterans With Treatment-resistant PTSD: A Longitudinal Follow-up Study https://pubmed.ncbi.nlm.nih.gov/36433746/
“Hyperbaric oxygen therapy (HBOT) induced neuroplasticity and improved clinical symptoms of veterans with treatment-resistant PTSD.”
“….The beneficial clinical effects of HBOT are persistent and were not attenuated at long-term follow-up of about 2 years after completion of HBOT. Additional long-term effects of the treatment were observed in social function and in decreased medication use.”
Hyperbaric Oxygen Therapy for Veterans With Combat-Associated Posttraumatic Stress Disorder: A Randomized, Sham-Controlled Clinical Trial https://pubmed.ncbi.nlm.nih.gov/39566051/
Hyperbaric oxygen therapy improves symptoms, brain’s microstructure and functionality in veterans with treatment resistant post-traumatic stress disorder: A prospective, randomized, controlled trial https://pubmed.ncbi.nlm.nih.gov/35192645/
“HBOT improved symptoms, brain microstructure and functionality in veterans with treatment resistant PTSD.”
Systematic review and dosage analysis: hyperbaric oxygen therapy efficacy in the treatment of posttraumatic stress disorder https://pubmed.ncbi.nlm.nih.gov/38882688/
“…..In multiple randomized and randomized controlled clinical trials HBOT demonstrated statistically significant symptomatic improvements, Reliable Changes, or Clinically Significant Changes in patients with PTSD symptoms or PTSD over a wide range of pressure and oxygen doses.”
“….Symptomatic improvements were supported by correlative functional and microstructural imaging changes in PTSD-affected brain regions. The imaging findings and hyperbaric oxygen therapy effects indicate that PTSD can no longer be considered strictly a psychiatric disease.”
Hyperbaric oxygen therapy for mild traumatic brain injury persistent postconcussion syndrome: a randomized controlled trial https://pubmed.ncbi.nlm.nih.gov/32189664/
“…..statistically significant improvements in postconcussion and Post-Traumatic Stress Disorder symptoms, memory, cognitive functions, depression, anxiety, sleep, and quality of life in civilian and military subjects with mTBI/PPCS compared to controls. Improvements persisted at least 2 months after the 40th HBOT.”
Effect of hyperbaric oxygen on post-stroke depression https://pubmed.ncbi.nlm.nih.gov/37303936/
“HBOT therapy can significantly improve depressive symptoms and neurological dysfunction in patients with PSD, and reduce the levels of hypersensitive C-reactive protein, TNF-α and fasting blood glucose.”
